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ORTHOCLONE OKT3
Descriptors Found:
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DeCS
Descriptor
English
:
Muromonab-CD3
Descriptor
Spanish
:
Muromonab-CD3
Descriptor
Portuguese
:
Muromonab-CD3
Synonyms
English
:
OKT3
Orthoclone OKT3
Muromonab CD3
Monoclonal Antibody OKT3
Tree Number:
D12.776.124.486.485.114.224.075.570
D12.776.124.486.485.114.619.393.570
D12.776.124.790.651.114.224.075.570
D12.776.124.790.651.114.619.393.570
D12.776.377.715.548.114.224.284.570
D12.776.377.715.548.114.619.393.570
Definition
English
:
Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti).
Indexing Annotation
English
:
do not coordinate with
ANTIBODY FORMATION
for biosyn
Pharmacological Action:
Immunologic Factors
Immunosuppressive Agents
History Note
English
:
92; MONOCLONAL ANTIBODY OKT3 was MONOCLONAL ANTIBODY OKT3, ORTHOCLONE (NM) 1987-91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
DT
drug therapy
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29952
Unique Identifier:
D016853
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS